Medical Neuropsychology and Behavioral Health

Edited by Cady Block and Doug Johnson-Greene
Foreword by Kenneth Adams

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May 30, 2025
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398 Pages
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It is increasingly recognized that medical conditions can have a range of neurocognitive, psychosocial, and functional implications, even in the absence of obvious neurological involvement. Filling a gap in the literature, this comprehensive clinical reference reviews current research and provides clear guidelines for assessment and intervention. Chapters organized around major bodily systems—for example, cardiovascular, endocrine, immune/lymphatic—probe neurocognitive impairments associated with prevalent health conditions and their treatments, including coverage of COVID-19. State-of-the-science chapters on lifestyle behaviors and habits explore the neurocognitive impact of sleep and fatigue, nutrition and weight, acute and chronic pain (and the use of opioid analgesics), personality and temperament, and substance misuse.

“This book is long overdue as a resource for clinical neuropsychologists. The volume rightfully recognizes that the brain does not work in isolation, but rather across and within systems throughout the body. This focus is particularly helpful in postdoctoral fellowship training, where burgeoning neuropsychologists enhance their existing clinical practice and research and get involved in innovative new applications in clinical neuroscience.”

—Beth K. Rush, PhD, ABPP, Department of Psychiatry and Psychology, Mayo Clinic Florida


“This impressive resource will be useful to practicing neuropsychologists and trainees, as well as clinical psychologists in medical settings. The volume covers a range of non-central nervous system conditions for which neuropsychologists have a role to play in evaluation, patient and family feedback, and clinical research. Some of the conditions covered have been less widely studied from a neuropsychological perspective, and chapters help set the stage for new directions and opportunities in multidisciplinary health care. The volume strikes a nice balance between foundational and more advanced information about interactions between neurobehavioral, cognitive, and psychological factors in different bodily systems.”

—C. Munro Cullum, PhD, ABPP, Professor of Psychiatry, Neurology, and Neurological Surgery; Pamela Blumenthal Distinguished Professor of Clinical Psychology; and Senior Neuropsychologist, Peter O’Donnell Brain Institute, University of Texas Southwestern Medical Center


“Block and Johnson-Greene provide a much-needed examination of how 'non-neurological' disorders impact neuropsychological function. Among the book's strengths are chapters on behavioral influences on brain health, in addition to the bodily systems-based chapters. The emphasis on structural and functional neuroanatomical correlates gives readers a critical foundation for making brain–behavior predictions based on a patient's medical history. The book also offers very useful practical recommendations, such as suggested interview questions and screening tests. This text is essential for all clinicians, from trainees to seasoned neuropsychologists, given the multiple medical comorbidities seen in patients who present for neuropsychological assessment.”

—Cynthia S. Kubu, PhD, ABPP-CN, Staff Neuropsychologist, Cleveland Clinic; Professor of Neurology and Vice Dean for Faculty, Case Western Reserve University School of Medicine


“Evidence amassed over decades in the clinical neuropsychology field has highlighted that the brain and body operate through complex relationships that are not unidirectional, but rather multidirectional. In this tour de force volume, expert contributors thoughtfully elucidate the bodily systems and modifiable external factors that play critical roles in adult brain health. This well-organized, highly instructive book elegantly synthesizes extensive scientific knowledge, making it an accessible and invaluable reference for trainees and practitioners at every career stage.”

—Shawn M. McClintock, PhD, MSCS, Lydia Bryant Test Distinguished Professorship in Psychiatric Research, University of Texas Southwestern Medical Center

Table of Contents

Foreword, Kenneth Adams

Preface

I. Bodily Systems

1. Cardiovascular, Elyssa A. Scharaga & Deborah B. Meehan

2. Respiratory, Robert J. Spencer & Elizabeth B. Campbell

3. Endocrine and Metabolic, Suzanne Penna

4. Digestive, Renal, and Hepatic, Jenessa S. Price

5. Immune/Lymphatic I—Autoimmune, Michael R. Basso, Douglas M. Whiteside, & Dennis C. Combs

6. Immune/Lymphatic II—Infectious, Steven Paul Woods, Jennifer L. Thompson, Michelle A. Babicz, Anastasia Matchanova, & Ilex A. Beltran-Najera

II. Behavioral Health and Lifestyle

7. Arousal, Sleep, and Fatigue, Malorie E. Watson, Benjamin Fusco-Gessick, Eric McConathey, Amy Z. Wang, & Molly Zimmerman

8. Weight and Nutrition, Marie Caillaud, Harley Layman, Misty A. W. Hawkins, & Andreana P. Haley

9. Acute and Chronic Pain, Benjamin D. Hill, Melissa Myers, & Jake Epker

10. Alcohol and Substance Use, Simon J. Scalzo, Candice Basterfield, & Stephen C. Bowden

11. Personality and Temperament, Julie A. Suhr & Andrew M. Bryant

Index


About the Editors

Cady Block, PhD, ABPP-CN, is Associate Professor in the Department of Psychiatry and Psychology at Mayo Clinic Florida. Previously, she served as training director for the neuropsychology practicum program and internship rotation at Emory University School of Medicine and as a clinical supervisor for the neuropsychology practicum program and internship rotation at The Ohio State University Wexner Medical Center. Dr. Block has published numerous peer-reviewed articles related to neuropsychology training, education, and practice, and has held leadership roles in national and international neuropsychological societies. She is a member of the board of KnowNeuropsychology, an international neuropsychology education/training initiative, and serves as Co-Director of New2Neuropsychology. Dr. Block is a recipient of the Early Career Service Award from the National Academy of Neuropsychology; the Presidential Citation Award and the Robert A. and Phyllis Levitt Early Career Award from the Society for Clinical Neuropsychology, Division 40 of the American Psychological Association; and the Early Career Champion Award and Raymond D. Fowler Award for Outstanding Contribution to the Professional Development of Graduate Students from the American Psychological Association.

Doug Johnson-Greene, PhD, MPH, ABPP-CN, is Professor, Director of Neuropsychology and Rehabilitation Psychology, and Associate Vice-Chair of Physical Medicine and Rehabilitation at the University of Miami Miller School of Medicine. He is a Diplomate of the American Board of Professional Psychology in the areas of Clinical Psychology, Rehabilitation Psychology, and Clinical Neuropsychology, and is a Fellow of the National Academy of Neuropsychology; the American Academy of Clinical Neuropsychology; and Divisions 12, 22, 40, and 50 of the American Psychological Association. Dr. Johnson-Greene has been practicing in academic medical centers since the 1990s and has trained over 100 medical and graduate students, postdoctoral fellows, and faculty. He has over 110 scholarly research publications on a wide range of topics. Dr. Johnson-Greene is a past board member of the American Academy of Clinical Neuropsychology and past president of the Society for Clinical Neuropsychology, Division 40 of the American Psychological Association, among numerous other professional leadership roles. His clinical interests include assessment and treatment of traumatic brain injury, substance abuse in persons with disabilities, and professional and ethical issues in clinical practice.

Audience

Neuropsychologists; clinical, rehabilitation, and health psychologists; psychiatrists; gerontologists; nurses; and allied health professionals.

Course Use

May serve as a supplemental text in graduate-level courses.