This forward-thinking volume grapples with critical questions surrounding the mechanisms underlying mental disorders and the systems used for classifying them. Edited and written by leading international authorities, many of whom are actively involved with the development of DSM-V and ICD-11, the book integrates biological and psychosocial perspectives. It provides balanced analyses of such issues as the role of social context and culture in psychopathology and the pros and cons of categorical versus dimensional approaches to diagnosis. Cutting-edge diagnostic instruments and research methods are reviewed. Throughout, contributors highlight the implications of current theoretical and empirical advances for understanding real-world clinical problems and developing more effective treatments.