“This book is excellent. Written by well-known experts, it covers many different DSM-5 disorders and problems, providing a step-by-step approach to treatment. The sixth edition justifies replacing the fifth because new research is released daily revealing new evidence-based treatments, as reflected by the updated content in this edition. Clinicians and researchers will not be disappointed by this volume….*****!”

—Doody's Review Service


“The Clinical Handbook succeeds in offering its readers procedures for assessment, case formulation, treatment planning, and intervention strategies and techniques. Clinical vignettes and transcripts populate the pages, which serve to exhibit the integration of theory, empiricism, and real-world practice. These clinical illustrations further demonstrate how proficient use of evidence-based practices involves the principled application of techniques individualized to meet patients’ needs instead of rigid adherence to manualized treatments. This realistic portrayal of the skill required to render treatments effectively is refreshing….A very well-written and easy to use textbook. As a reference resource, it will serve students and therapists like a favorite cookbook…as they return to seek clinical recipes that will help them better serve their patients.”

—Journal of Clinical Psychiatry (on the fifth edition)


“An outstanding revision. Each chapter is well organized, and includes a comprehensive range of information. This handbook is a helpful resource for keeping mental health professionals and students up to date on the latest research and advances in evidence-based treatments for commonly encountered psychological disorders.”

—Journal of Psychiatric Practice (on the fifth edition)


“An indispensable guide replete with clinical tools for new and seasoned clinicians, as well as an excellent teaching resource….The authors, all distinguished scholars and clinical investigators, have addressed a wide range of psychological disorders in a rigorous and empirical manner, skillfully translating what is known about them, from theory and precisely executed research to clinical application.…An exceptional resource for clinicians and should be required reading for all in mental health training programs. It has surpassed its stated objectives to provide state-of-the-art scientific knowledge, present empirically tested effective therapies, and teach clinicians how to implement these treatments in a step-by-step manner, helping them achieve the goal that every mental health professional seeks to achieve, that is, to alleviate psychological pain and enable every client to live a more gratifying and fulfilling life.”

—Journal of Nervous and Mental Disease (on the fifth edition)


“The sixth edition of Barlow's handbook is an essential resource for anyone wanting a deep dive into the latest developments in evidence-based practice for a wide variety of clinical concerns. Twenty-five years after formalizing the evidence-based practice movement within clinical psychology, Barlow has once again masterfully curated an up-to-date reference written by the field's leading clinical scientists. The sixth edition offers fresh insights, critical advances, and rich examples. Whether you are a graduate student, a clinical researcher, or a seasoned practitioner, this book should always be within arm's reach.”

—Bruce F. Chorpita, PhD, Department of Psychology, University of California, Los Angeles; President, PracticeWise


“I have used this valuable text in my graduate classes since the first edition was published in 1985. Chapters present concise summaries of the theory and empirical evidence for the respective interventions, along with insightful explanations of how they are conducted. With the sixth edition, Barlow has again provided a rare gem that helps students and practicing clinicians understand how evidence-based treatments are actually implemented with clients. The book includes updated chapters on well-established approaches presented in previous editions, as well as more recent developments, such as process-based therapy and the transdiagnostic treatment of self-injurious thoughts and behaviors.”

—Leonard A. Doerfler, PhD, Professor and Director, Clinical Counseling Psychology Program, Assumption University


“A marvelous presentation of the latest and most clinically applicable evidence-based practices, including cognitive, behavioral, and interpersonal approaches. Revised and new chapters are written by the best and brightest in the field, including many of those who developed the respective interventions. The sixth edition of the Handbook is suitable for both students in training and experienced practitioners who want to burnish their clinical skills. There is no better collection that highlights how the field developed, where it currently is, and where it is going to be in the future. I could not recommend it more strongly.”

—Steven D. Hollon, PhD, Gertrude Conaway Vanderbilt Professor of Psychology, Vanderbilt University


“In its sixth edition, this handbook continues to be the single best teaching text on evidence-based practices in mental health. I use this book as a primary text and resource in my Advanced Clinical Practice class and my students rarely resell it—they take it with them when they graduate to save as a clinical reference. The chapter organization makes the book ideal for teaching beginning clinicians. Having a regularly revised text that navigates this increasingly sophisticated and complex terrain makes both the students and me feel like we have a partner in their learning.”

—André Ivanoff, PhD, Columbia University School of Social Work


“Since its initial publication, this handbook has been the single most important volume on evidence-based psychotherapy. For the sixth edition, as in prior editions, Barlow has assembled eminent contributors who are expert practitioners of the therapies they discuss. Each chapter features a review of the evidential basis for the therapy, a description of its implementation, and a detailed clinical illustration. The authors skillfully demonstrate the flexible application of our most efficacious protocols as they merge clinical wisdom and the best psychological science. Essential reading for all mental health professionals, this is the ideal text for graduate psychotherapy courses, and the one we have always used in Harvard's clinical psychology program.”

—Richard J. McNally, PhD, Professor and Director of Clinical Training, Department of Psychology, Harvard University