I. Ethics Approval

1. When Mountains Move Too Slowly, Melanie A. Hwalek and Victoria L. Straub

2. The Ethics of Sex Research on the Internet, Alissa Sherry and Amy Amidon

3. When Safeguards Become Straitjackets: How Ethics Research Board Requirements Might Contribute to Ethical Dilemmas in Studies with Marginalized Populations, Mechthild Meyer, Alma Estable, Lynne MacLean, and Nancy Edwards

4. Going Off the Rails for “Love or Money”: Implementation Issues Related to Payment of Research Participants in an Addiction-Research Project, Brian R. Rush and Dominique Morisano

II. Accessing the Participants

5. Frailty, Thy Name Is Macho, José Quirino dos Santos

6. Power in Numbers: Research with Families in Long-Term Care, Julie M. Dergal Serafini

7. Getting the Wrong Gatekeeper, Lynne MacLean

8. Breaking into Court, Mandeep K. Dhami and Karen A. Souza

9. The RDC Archipelago, Scott Veldhuizen, John Cairney, and David L. Streiner

III. Recruitment and Retention

10. Small Colleges and Small n’s, Christopher Koch and Anna Tabor

11. Mitigating the Impact of External Forces, Souraya Sidani, David L. Streiner, and Chantale Marie LeClerc

12. A Trip to the School of Hard Knocks: Recruiting Participants from Health Service Agencies for Qualitative Studies of Aging, Kathleen W. Piercy

13. All Aboard!: Using Community Leaders to Keep Clinical Researchers on Track, Philippe Barrette

14. Changing Horses in Midstream: Transforming a Study to Address Recruitment Problems, Anthony S. Joyce

15. When Cost Meets Efficiency: Rethinking Ways to Sample a Rare Population, Julian Montoro-Rodriguez and Gregory C. Smith

16. The Story Is in the Numbers, Robert van Reekum

17. Strategies for Retaining Participants in Longitudinal Research with Economically Disadvantaged and Ethnically Diverse Samples, Elizabeth A. Goncy, Michelle E. Roley, and Manfred H. M. van Dulmen

18. Culturally Specific Strategies for Retention and Adherence to Physical Activity Interventions in Hispanic Women, Colleen Keller, Julie Fleury, and Adrianna Perez

IV. Study Implementation

19. When a Beautiful Intervention Meets Ugly Reality: Implementing an Intervention in the Real World, Souraya Sidani, David L. Streiner, and Chantale Marie LeClerc

20. When Saving Blood Goes Wrong, Claudio S. Cinà and Catherine M. Clase

21. PDA = Pretty Darned Awful: The Trials and Tribulations of Running Trials of PDAs, Geoffrey R. Norman

22. When Sugar Is Not So Sweet: Camera Shyness and Intentional Cointervention Almost Derail a Study, Françoise Filion and C. Celeste Johnston

23. Placebo Problems: Power and Persecution, or Paranoia?, Robert van Reekum

V. Data Collection

24. Revisiting Traditional Survey Methodology to Recruit and Survey Lesbian, Gay, and Bisexual Older Adults, S. Melinda Spencer and Julie Hicks Patrick

25. Technology: Help or Hindrance?, Nasreen Roberts

26. Hoist on Our Own Postcard, David L. Streiner

27. On the Finer Points of Handling Googlies: Reflections on Hits, Near Misses, and Full-Blown Swings at the Air in Large, Population-Based Studies Involving School, Parents, and Children, John Cairney, John A. Hay, and Brent E. Faught

28. Pets, Pies, and Videotape: Conducting In-Home Observational Research with Late-Life Intergenerational Families, Brian D. Carpenter and Steve Balsis

29. Underfunded but Not Undone, Dianne Bryant

30. Community-Based Participatory Research: A Lesson in Humility, Dennis Watson

31. Where Did All the Bodies Go?, Harry S. Shannon

32. Measures for Improving Measures, Katherine McKnight, and Patrick E. McKnight

VI. Data Analysis

33. Drowsing Over Data: When Less Is More, Lynne MacLean, Alma Estable, Mechthild Meyer, Anita Kothari, Nancy Edwards, and Barb Riley

34. Bigger Is Not Always Better: Adventures in the World of Survey Data Analysis, Sylvia Kairouz and Louise Nadeau

35. Taking Aim at a Moving Target: When a Study Changes in the Middle, Arturo Martí-Carvajal

36. Lack of Normative Data as an Obstacle to Neuropsychological Assessment, F. Richard Ferraro and Kaylee Trottier-Wolter

37. These Data Do Not Compute, Lynne MacLean, Mechthild Meyer, Alma Estable, Anita Kothari, and Nancy Edwards

38. Avoiding Data Disasters and Other Pitfalls, Melinda F. Davis

39. When Interpretation Goes Awry: The Impact of Interim Testing, Dale Glaser

VII. Collaboration

40. What Happened to Cooperation and Collaboration?, Nasreen Roberts

41. Presto! It’s Gone: When a Study Ceases to Exist Right before Your Eyes, Katrina L. Bledsoe

42. Building Stakeholder Capacity to Enhance Effectiveness in Participatory Program Evaluation, Debazou Y. Yantio

VIII. Final Thoughts

43. Sometimes It Is the Researcher, Not the Research, That Goes “Off the Rails”: The Value of Clear, Complete, and Precise Information in Scientific Reports, Joseph A. Durlak, Christine I. Celio, Molly K. Pachan, and Kriston B. Schellinger

44. A Healthy Dose of Realism, Souraya Sidani and David L. Streiner